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Sodium butyrate inhibits expression of urokinase and its receptor mRNAs at both transcription and post-transcription levels in colon cancer cells

โœ Scribed by Jinjun Dang; Yao Wang; William F. Doe


Book ID
115930435
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
480 KB
Volume
359
Category
Article
ISSN
0014-5793

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Amiloride modulates urokinase gene expre
โœ Yao Wang; Jinjun Dang; Xiaoming Liang; William F. Doe ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› Springer ๐ŸŒ English โš– 666 KB

Activity of receptor-bound urokinase plasminogen activator (uPA) on the surface of colon cancer cells appears to be a function of the number of uPA receptors. The regulation of uPA therefore may determine the invasive phenotype. The effects of amiloride on the modulation of uPA mRNA and protein indu