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Sodium borohydride on wet clay: Solvent-free reductive amination of carbonyl compounds using microwaves

✍ Scribed by Rajender S. Varma; Rajender Dahiya

Publisher
Elsevier Science
Year
1998
Tongue
French
Weight
392 KB
Volume
54
Category
Article
ISSN
0040-4020

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✦ Synopsis

A solvent-free reductive amination of carbonyl compounds by wet montmorillonite K 10 clay supported sodium borohydride is described; microwave irradiation facilitates the procedure.

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## Abstract A novel protocol for the fast and efficient reductive amination of carbonyl compounds (25 examples) is developed that is comparable with various reducible functional groups such as NO~2~‐ and CN‐groups as well as C=C double bonds.