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Sodium arsenite induces ROS-dependent autophagic cell death in pancreatic β-cells

✍ Scribed by Zhu, Xue-Xin; Yao, Xiao-Feng; Jiang, Li-Ping; Geng, Cheng-Yan; Zhong, Lai-Fu; Yang, Guang; Zheng, Bai-Lu; Sun, Xian-Ce


Book ID
124109032
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
1019 KB
Volume
70
Category
Article
ISSN
0278-6915

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## Abstract Previous studies reported that high levels of nitric oxide (NO) induce apoptotic cell death in osteoblasts. We examined molecular mechanisms of cytotoxic injury induced by sodium nitroprusside (SNP), a NO donor, in both glutathione (GSH)‐depleted and control U2‐OS osteoblasts. Cell viab