Sodium and potassium channels in epithelial cells from thymus glands and thymomas of myasthenia gravis patients

✍ Scribed by A. Marx; J. Siara; R. Rüdel

• Publisher: Springer
• Year: 1991
• Tongue: English
• Weight: 325 KB
• Volume: 417
• Category: Article
• ISSN: 0031-6768
• DOI: 10.1007/bf00370951

✦ Synopsis

In both normal and neoplastic epithelial cells from human thymus glands and thymomas, respectively, we found voltage-gated sodium and potassium channels that resemble the adult-type Na channel and the delayed outward rectifier K channel, respectively, of human skeletal muscle and mammalian nervous system. These voltage-gated ion channels might be part of a communication system between epithelial cells and other components of the microenvironment of the thymus.