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SOD1 mRNA expression in sporadic amyotrophic lateral sclerosis

✍ Scribed by Stella Gagliardi; Emanuela Cova; Annalisa Davin; Stefania Guareschi; Kenneth Abel; Elena Alvisi; Umberto Laforenza; Roberta Ghidoni; John Richard Cashman; Mauro Ceroni; Cristina Cereda


Book ID
113812484
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
658 KB
Volume
39
Category
Article
ISSN
0969-9961

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## Abstract Amyotrophic lateral sclerosis (ALS) is the most common fatal motor neuron disease. It has been generally accepted that the proapoptotic property of the familial ALS (FALS)‐linked mutant __SOD1__ genes plays an important role in the pathogenesis of some FALS cases. We found here that exp