CYP17 polymorphisms in relation to risks
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M. Patricia Madigan; Yu-Tang Gao; Jie Deng; Ruth M. Pfeiffer; Bao-Li Chang; Siqu
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Article
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2003
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John Wiley and Sons
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French
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## Abstract Because androgens likely play a key role in prostate growth and prostate cancer development, variants of genes involved in androgen biosynthesis may be related to prostate cancer risk. The enzyme P450c17ฮฑ, encoded by the __CYP17__ gene, catalyzes the conversion of progesterone and pregn