✦ LIBER ✦

SNS-314, a pan-Aurora kinase inhibitor, shows potent anti-tumor activity and dosing flexibility in vivo

✍ Scribed by Jennifer P. Arbitrario; Brian J. Belmont; Marc J. Evanchik; W. Michael Flanagan; Raymond V. Fucini; Stig K. Hansen; Shannon O. Harris; Ahmad Hashash; Ute Hoch; Jennifer N. Hogan; Anthony R. Howlett; Jeffrey W. Jacobs; Joni W. Lam; Sean C. Ritchie; Michael J. Romanowski; Jeffrey A. Silverman; David E. Stockett; Juli N. Teague; Kristin M. Zimmerman; Pietro Taverna

Book ID: 105993222
Publisher: Springer
Year: 2009
Tongue: English
Weight: 453 KB
Volume: 65
Category: Article
ISSN: 0344-5704
DOI: 10.1007/s00280-009-1076-8

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

502 POSTER SNS-314, a selective Aurora k

502 POSTER SNS-314, a selective Aurora kinase inhibitor with potent, pre-clinical antitumour activity, shows broad therapeutic potential in combination with standard chemotherapeutics and synergy with microtubule targeted agents

✍ E. Chan; R. Fucini; K. Zimmerman; M. Bui; J. Hogan; M. Jackson; P. Taverna; A. H 📂 Article 📅 2007 🏛 Elsevier Science 🌐 English ⚖ 57 KB

119 ARQ 087: A potent ATP-independent fi

119 ARQ 087: A potent ATP-independent fibroblast growth factor receptor (FGFR) kinase inhibitor showing in vivo anti-tumor activity in FGFR2-driven tumors

✍ C.R. Chen; S. Ali; E. Nakuci; D. McSweeney; J.O. Brown; J. Szwaya; C. Bull; R. S 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 63 KB

493 AS703569/R763, a pan Aurora kinase i

493 AS703569/R763, a pan Aurora kinase inhibitor, shows strong antitumor activity in vitro and in vivo in a panel of triple-negative breast cancer cell lines and xenografts

✍ E. Marangoni; A. Clark; F. Assayag; S. Chateau-Joubert; A. Hamini; M.F. Poupon; 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 64 KB

The pan-ErbB receptor tyrosine kinase in

The pan-ErbB receptor tyrosine kinase inhibitor canertinib promotes apoptosis of malignant melanoma in vitro and displays anti-tumor activity in vivo

✍ Emelie A. Djerf Severinsson; Cecilia Trinks; Henrik Gréen; Avni Abdiu; Anna-Lott 📂 Article 📅 2011 🏛 Elsevier Science 🌐 English ⚖ 693 KB

1110 POSTER BPR1K653, a Novel Aurora Kin

1110 POSTER BPR1K653, a Novel Aurora Kinase Inhibitor, Exhibits Potent Anti-proliferative Activity in P-gp170 (MDRI)-mediated VX680-resistant Cancer Cells in Vitro and in Vivo

✍ H.P. Hsieh; C.H.A. Cheung; W.H. Lin; T.A. Hsu; M.S. Coumar; Y.S. Chao; J.Y. Chan 📂 Article 📅 2011 🏛 Elsevier Science 🌐 English ⚖ 42 KB