SNP Discovery and Haplotype Analysis in the Segmentally Duplicated DRD5 Coding Region
โ Scribed by Donna J. E. Housley; Molly Nikolas; Patrick J. Venta; Kathrine A. Jernigan; Irwin D. Waldman; Joel T. Nigg; Karen H. Friderici
- Book ID
- 111111491
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 233 KB
- Volume
- 73
- Category
- Article
- ISSN
- 0003-4800
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract Modern molecular techniques make discovery of numerous single nucleotide polymorphims (SNPs) in candidate gene regions feasible. Conventional analysis relies on either independent tests with each variant or the use of haplotypes in association analysis. The first technique ignores the d
Dysfunction of serotonin systems has been implicated in schizophrenia. In the present study, the human 5-HT 1A receptor gene containing the 5 untranslated region was screened in order to detect genetic variations, through which alteration of protein function or level of expression might contribute t