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SNP-based prediction of the human germ cell methylation landscape

✍ Scribed by Hehuang Xie; Min Wang; Jared Bischof; Maria de Fatima Bonaldo; Marcelo Bento Soares


Book ID
116981847
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
459 KB
Volume
93
Category
Article
ISSN
0888-7543

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## Abstract Previous studies have demonstrated biallelic expression of the imprinted genes __H19__ and __IGF2__ and loss of DNA methylation of the __SNRPN__ gene, indicating a common precursor cell of human germ cell tumors (GCTs), namely, the primordial germ cell (PGC). In this study, we applied t