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SnCl2 · 2H2O-catalyzed one-pot synthesis of 4(3H)-quinazolinones from anthranilic acid, ortho esters, and amines under solvent free conditions

✍ Scribed by Min Wang; Zhiguo Song; Tingting Zhang


Publisher
Journal of Heterocyclic Chemistry
Year
2010
Tongue
English
Weight
74 KB
Volume
47
Category
Article
ISSN
0022-152X

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✦ Synopsis


Abstract

magnified image A simple, efficient, and green procedure for the one‐pot synthesis of 4(3__H__)‐quinazolinones by three components condensation of anthranilic acid, ortho esters, and amines in the presence of SnCl~2~ · 2H~2~O has been developed. The reaction occurred within short reaction time at room temperature under solvent‐free conditions to afford the title products in excellent yields. J. Heterocyclic Chem., (2010).


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