SN2 at nitrogen: The reaction of N-(4-cy
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RΓΌdiger Ulbrich; Michael Famulok; Ferdinand Bosold; Gernot Boche
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Article
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1990
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Elsevier Science
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French
β 254 KB
Tbe model reaction of 5 with 6 to give 7 and 8 (>90%) follows the SN~ mechankm. From this result and from product studies it is concluded that the reactions of the ultimate carcinogen 1 with 6 and deoxy8uanosine (dG) (and hence of other ultimate carcino8ens of aromatic amines with biot.mckophiles) f