✦ LIBER ✦

SN2′ Reaction of Organozinc Reagents Activated by Catalytic tBu-P4 Base in the Presence of LiCl

✍ Scribed by Koji Kobayashi; Masahiro Ueno; Hiroshi Naka; Yoshinori Kondo

Publisher: John Wiley and Sons
Year: 2009
Tongue: English
Weight: 289 KB
Volume: 15
Category: Article
ISSN: 0947-6539
DOI: 10.1002/chem.200900556

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

The __t__Bu‐P4 base was found to be an excellent catalyst for the activation of organozinc reagents. The base was used to promote the S~N~2′ reaction of α,β‐unsaturated esters bearing a γ‐chloride in the reactions with various organozinc reagents in the presence of LiCl. The reactions proceeded in high yield with excellent chemo‐and regioselectivity. The role of LiCl appears to be the activation of the γ‐chloride of the α,β‐unsaturated esters, which was confirmed by NMR spectroscopic study.

📜 SIMILAR VOLUMES

ChemInform Abstract: Activation of Organ

ChemInform Abstract: Activation of Organozinc Reagents with t-Bu-P4 Base for Transition Metal-Free Catalytic SN2′ Reaction.

✍ Koji Kobayashi; Masahiro Ueno; Hiroshi Naka; Yoshinori Kondo 📂 Article 📅 2008 🏛 John Wiley and Sons ⚖ 40 KB

Activation and Deactivation by Temperatu

Activation and Deactivation by Temperature: Behavior of Ph2PN(iPr)P(Ph)N(iPr)H in the Presence of Alkylaluminum Compounds Relevant to Catalytic Selective Ethene Trimerization

✍ Stephan Peitz; Dr. Normen Peulecke; Dr. Bhaskar R. Aluri; Dr. Bernd H. Müller; D 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 398 KB

ChemInform Abstract: Synthesis and Chara

ChemInform Abstract: Synthesis and Characterization of New (N-Diphenylphosphino)-isopropylanilines and Their Complexes: Crystal Structure of (Ph2P=S)NH—C6H4—4-CH (CH3)2 and Catalytic Activity of Palladium(II) Complexes in the Heck and Suzuki Cross-Coupling Reactions.

✍ Murat Aydemir; Akin Baysal; Nevin Guerbuez; Ismail Oezdemir; Bahattin Guemguem; 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 32 KB 👁 1 views