SN2′ Alkylation of Chiral Allylic Cyanoh
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Alejandro Baeza; Carmen Nájera; José M. Sansano
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Article
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2007
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John Wiley and Sons
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English
⚖ 213 KB
## Abstract Enantiomerically enriched cyanohydrin __O__‐phosphates, prepared by enantioselective cyanophosphorylation of α,β‐unsaturated aldehydes, react regioselectively at the γ‐position with organocuprates derived from alkyl Grignard reagents and CuCN to afford chiral γ‐alkyl‐substituted α,β‐uns