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SN 1 and SN 2 mechanisms for the deprotection of synthetic peptides by hydrogen fluoride

✍ Scribed by TAM, JAMES P. ;HEATH, WILLIAM F. ;MERRIFIELD, R.B.


Book ID
115098042
Publisher
Wiley (Blackwell Publishing)
Year
2009
Tongue
English
Weight
629 KB
Volume
21
Category
Article
ISSN
0367-8377

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The rate data for the Menschutkin reaction between strongly activated Z-substituted benzyl ptoluenesulfonates and Y-substituted N,N-dimethylanilines in acetonitrile at 35 Β°C fit the equation, , which is consistent with concurrent first-and second-order processes. The k 1 and k 2 values for each sub