Smooth muscle development in the obstructed fetal bladder
โ Scribed by Andrew L. Freedman; Faisal Qureshi; Ellen Shapiro; Herbert Lepor; Suzanne M. Jacques; Mark I. Evans; Craig A. Smith; Ricardo Gonzalez; Mark P. Johnson
- Book ID
- 119486623
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 494 KB
- Volume
- 49
- Category
- Article
- ISSN
- 0090-4295
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We evaluated compliance in the developing bladder using a newly developed animal model of posterior urethral valves: partial infravesical obstruction in the fetal rabbit bladder. Partial bladder outlet obstruction was created in fetal rabbits at day 23 of a 31 to 32-day gestation period. An in vitro
Partial bladder outlet obstruction results in progressive loss in contractile and specific cellular and subcellular membrane functions. There is evidence that ischemic activation of proteolytic and lipolytic enzymes play a major role in the etiology of bladder dysfunction secondary to partial outlet