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Smoking, fat mass and activation of the tumor necrosis factor-α pathway

✍ Scribed by Fernandez-Real, J-M; Broch, M; Vendrell, J; Ricart, W


Book ID
110045347
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
115 KB
Volume
27
Category
Article
ISSN
1476-5497

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## Electrospray ionization mass spectrometry (ESI-MS ) is employed to directly analyze the limited trypsinolysis products of wild-type tumor necrosis factor-␣ (wtTNF-␣) and its mutant, M3S. To determine the charge numbers of peaks of relatively small peptides in the ESI mass spectrum of a digest,