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Smoking does not alter the dose-requirements and the pharmacodynamics of rocuronium

✍ Scribed by Friedrich K. Pühringer; Philipp Keller; Alexander Löckinger; Axel Kleinsasser; Annkatrin Scheller; Claus Raedler; Christian Keller


Publisher
Springer-Verlag
Year
2000
Tongue
French
Weight
71 KB
Volume
47
Category
Article
ISSN
1496-8975

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## Abstract Rats were treated for 12 months with L‐dopa (191.4–210.4 mg/kg/day) plus carbidopa (23.9–26.2 mg/kg/day), or carbidopa (24.4–26.3 mg/kg/day) alone. Four days after drug withdrawal, animals received an acute challenge with either L‐dopa (50 mg/kg p.o.) alone or following acute carbidopa