✦ LIBER ✦

Smoking and schizophrenia

✍ Scribed by Joseph P. McEvoy; John Lindgren

Publisher: John Wiley and Sons
Year: 1996
Tongue: English
Weight: 337 KB
Volume: 38
Category: Article
ISSN: 0272-4391
DOI: 10.1002/(sici)1098-2299(199607/08)38:3/4<263::aid-ddr15>3.0.co;2-#

No coin nor oath required. For personal study only.

✦ Synopsis

Patients with schizophrenia smoke at a higher prevalence rate (80%) than the general population (30%). Those patients with schizophrenia who smoke have an earlier age of onset and may have more refractory psychopathology. Smoking improves sensory gating, sustained attention, and cognitive performance in patients with schizophrenia.

Conventional antipsychotic drugs initially increase smoking, Switching to the atypical antipsychotic, clozapine, decreases smoking. Smoking decreases the bioavailability of many antipsychotic drugs.

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