Smiles Rearrangement as a Tool for the Preparation of Dihydrodipyridopyrazines
✍ Scribed by Patriciu, Oana-Irina; Fînaru, Adriana-Luminita; Massip, Stéphane; Leger, Jean-Michel; Jarry, Christian; Guillaumet, Gérald
- Book ID
- 111951882
- Publisher
- American Chemical Society
- Year
- 2009
- Tongue
- English
- Weight
- 402 KB
- Volume
- 11
- Category
- Article
- ISSN
- 1523-7060
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In the preparation of 5-[(2-hydroxyacyl)amino]-2,4,6-triiodo-l,3-benzenedicartmxamides la-h from 2a-h two conditions using stoichiometric amounts of base (method A -aq NaOH at 50 °C; method B -MeONa in DMF at r. t.) were used. Yields are good to excellent provided that the right conditions are chose
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