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SmI2-mediated reductive enolization of α-hetero-substituted ketones and enantioselective protonation

✍ Scribed by Yutaka Nakamura; Seiji Takeuchi; Yoshiaki Ohgo; Makoto Yamaoka; Akihiro Yoshida; Koichi Mikami

Book ID
104256802
Publisher
Elsevier Science
Year
1997
Tongue
French
Weight
171 KB
Volume
38
Category
Article
ISSN
0040-4039

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✦ Synopsis

High enantioselectivity (tq9 to 94% ee) ha~ been trhieved in the protonation of samarium enolaes which were generated by S ml2-medaed nub, ction of 2-aryl-2-methoxycyclohexanones using a C2-symmetric chiraldiol as aproton source.

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