Smart Materials for Tissue Engineering: Applications

✍ Scribed by Badylak, Stephen F.; Cao, Zhiqiang; Coffer, Jeffery L.; Schneider, Hans-Jorg; Shahinpoor, Mohsen; Vamvakaki, Maria; Wang, Qun; Xu, Chenjie; Xu, Xiaoyang; Zhao, Qiang

• Publisher: Royal Society of Chemistry
• Year: 2017
• Tongue: English
• Leaves: 713
• Series: Smart Materials Series
• Edition: 1
• Category: Library

✦ Synopsis

In the last couple of decades, research in the area of tissue engineering has witnessed tremendous progress. The focus has been on replacing or facilitating the regeneration of damaged or diseased cell, tissue or organs by applying a biomaterial support system, and a combination of cells and bioactive molecules. In addition new smart materials have been developed which provide opportunities to fabricate, characterize and utilize materials systematically to control cell behaviours and tissue formation by biomimetic topography that closely replicate the natural extracellular matrix. Following on from Smart Materials for Tissue Engineering: Fundamental Principles, this book comprehensively covers the different uses of smart materials in tissues engineering, providing a valuable resource for biochemists, materials scientists and biomedical engineers working in industry and academia

✦ Table of Contents

Content: Cover
Smart Materials for Tissue Engineering: Applications
Foreword
Preface
Contents
Chapter 1 --
Applications of Smart Multifunctional Tissue Engineering Scaffolds
1.1 Introduction
1.2 Applications of Multifunctional Scaffolds in Tissue Engineering
1.2.1 Bone and Cartilage
1.2.1.1 Natural Polymers
1.2.1.2 Synthetic Polymers
1.2.1.3 Inorganic Materials
1.2.1.4 Hybrid Polymer/Inorganic Materials
1.2.1.5 Hybrid Synthetic/Natural Polymers
1.2.2 Muscle
1.2.3 Skin Tissue Engineering
1.2.4 Cardiovascular
1.2.4.1 Surface Coatings to Enhance Endothelialization 1.2.4.2 Tissue Engineered Cardiovascular Devices1.2.5 Neural Tissue Engineering
1.3 Clinical Potential and Applications of Multifunctional Scaffolds in Tissue Engineering
1.4 Conclusions
References
Chapter 2 --
Translational Smart Materials in Tissue Engineering
2.1 Introduction
2.2 Considerations of Smart Materials in Tissue Engineering
2.2.1 Biocompatibility
2.2.2 Structure
2.3 Classification of Smart Materials in Tissue Engineering
2.3.1 Synthetic Materials
2.3.2 Biosynthetic Materials
2.3.3 Biologic Materials
2.3.3.1 Protein-Based Materials 2.3.3.2 Polysaccharide-Based Materials2.3.3.3 ECM Materials
2.3.3.3.1 Modulation of the Immune Response.Macrophages play an essential role in tissue remodeling following implantation of an ECM scaff...
2.3.3.3.2 Degradation of ECM Scaffold Materials.Normal tissue exists in a dynamic state and includes processes of degradation and remodeli...
2.3.3.3.3 Cell Infiltration on ECM Bioscaffolds.The role of the ECM scaffolds and their degradation products is not limited to the immunom...
2.4 Clinical Translation of Smart Material for Tissue Engineering 2.5 Future Challenges for Translation of Smart Biomaterials in Tissue EngineeringReferences
Chapter 3 --
Applications of Injectable Smart Materials in Tissue Engineering
3.1 Introduction
3.2 Stimuli-Responsive Injectable Polymeric Hydrogels
3.2.1 Temperature-Responsive Injectable Hydrogels
3.2.2 pH-Responsive Injectable Hydrogels
3.2.3 Enzyme-Responsive Injectable Hydrogels
3.2.3.1 Sol-to-Gel Transition
3.2.3.2 Gel-to-Sol Transition
3.3 Injectable Supramolecular Hydrogels
3.4 Application of Injectable Smart Materials for Tissue Repair and Regeneration
3.4.1 Bone
3.4.2 Cartilage 3.4.3 Skin3.4.4 Cardiovascular
3.4.5 Skeletal Muscle and Tendon
3.5 Conclusion and Perspective
References
Chapter 4 --
Advances in Silicon Smart Materials for Tissue Engineering
4.1 Introduction
4.2 Fundamentals of Porous Silicon (pSi)
4.2.1 Porous Silicon (pSi) Can Be Processed into a Variety of Shapes and Forms
4.2.2 Control Over Pore Structure
4.2.3 Surface Chemistry
4.2.4 Cell Attachment and Differentiation on Porous Silicon
4.2.5 Advantages of pSi/Polymer Composites as Implants for Tissue Engineering
4.3 Porous Silicon as a "Smart" Biomaterial

✦ Subjects

Biomedical materials.;Smart materials.;Tissue engineering.