Small-vessel disease in patients with Parkinson's disease: A clinicopathological study
β Scribed by Raymond S. Schwartz; Glenda M. Halliday; Dennis J. Cordato; Jillian J. Kril
- Book ID
- 115559997
- Publisher
- John Wiley and Sons
- Year
- 2012
- Tongue
- English
- Weight
- 559 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0885-3185
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## Abstract Nonmotor symptoms (NMS) are increasingly recognized as a significant cause of morbidity in later stages of Parkinson's disease (PD). Prodromal NMS are also a well recognized component of the clinical picture in some patients but the prevalence of NMS as presenting complaints, and their
We describe the clinicopathological findings in a patient aged 63 years at death who, at age 55 years, developed levodopa-responsive parkinsonism with no atypical features. A diagnosis of idiopathic Parkinson's disease (PD) was made. During the clinical course, fluctuations and dyskinesias appeared.
We have read with interest the study by Santangelo et al., 1 reporting the role of vascular pathology in the neuropsychological profile of parkinsonian patients. The authors evaluated whether the brain's vascular lesion load is associated with neuropsychological variables. They compared the neuropsy