𝔖 Bobbio Scriptorium
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Small steps for humankind, a giant leap to Mars


Book ID
122832977
Publisher
Reed Business
Year
2009
Tongue
English
Weight
90 KB
Volume
203
Category
Article
ISSN
0262-4079

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Giant leap for p53, small step for drug
✍ Mary E. Anderson; Peter Tegtmeyer πŸ“‚ Article πŸ“… 1995 πŸ› John Wiley and Sons 🌐 English βš– 629 KB

## Abstract We review the findings of Cho __et al.__^(1)^ on the crystal structure of a p53 tumor suppressor‐DNA complex. The core DNA binding domain of p53 folds into a structure termed a β‐sandwich, which organizes two loops and a loop‐sheet‐helix structure on one surface of p53 to interact with