Current and voltage-clamp techniques were used to study the effects of kainic (KA) and quisqualic (quis) acids on the slow synaptic inhibition evoked by mossy fibre stimulation in CA3 hippocampal pyramidal neurones in vitro. The K + conductance underlying the slow synaptic inhibition is coupled to a
Small (SKCa) Ca2+-activated K+channels in cultured rat hippocampal pyramidal neurones
β Scribed by A. A. Selyanko; J. A. Sim; D. A. Brown
- Publisher
- Springer
- Year
- 1998
- Tongue
- English
- Weight
- 68 KB
- Volume
- 437
- Category
- Article
- ISSN
- 0031-6768
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Ca^2+^ channels and pyramidal cell Ca^2+^ are involved in hippocampal spreading depression (SD), but their roles remain elusive. Accordingly, we characterized Ca^2+^ changes during SD in CA3 pyramidal neurons and determined whether Ca^2+^ channel antagonists could prevent SD. SD was ind
Ca 2Ο© /calmodulin-dependent protein kinase IV (CaM kinase IV) is a multifunctional enzyme that is abundantly present in the nuclei of neurons. We report the properties of phosphorylation and activation of CaM kinase IV in comparison to CaM kinase II in cultured rat hippocampal neurons. Phosphorylati
Exploring the principles that govern activity-dependent changes in excitability is an essential step to understand the function of the nervous system, because they act as a general postsynaptic control mechanism that modulates the flow of synaptic signals. We show an activity-dependent potentiation