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Small Peptide-Catalyzed Enantioselective Addition of Ketones to Nitroolefins

✍ Scribed by Yongmei Xu; Weibiao Zou; Henrik Sundén; Ismail Ibrahem; Armando Córdova


Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
126 KB
Volume
348
Category
Article
ISSN
1615-4150

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Enantioselective Michael Addition of Aro
✍ Bai-Lin Li; Yi-Feng Wang; Shu-Ping Luo; Ai-Guo Zhong; Zhao-Bo Li; Xiao-Hua Du; D 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 774 KB

## Abstract A highly enantioselective Michael reaction of aromatic ketones with nitroolefins was accomplished in the presence of a chiral bifunctional primary amine–thiourea catalyst and 4‐nitrobenzoic acid as the co‐catalyst; the corresponding adducts were obtained in excellent enantioselectivitie