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Small-Molecule Inhibitors of Sodium Iodide Symporter Function

โœ Scribed by Nathalie Lecat-Guillet; Goulven Merer; Roman Lopez; Thierry Pourcher; Bernard Rousseau; Yves Ambroise


Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
376 KB
Volume
9
Category
Article
ISSN
1439-4227

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## Abstract The sodium iodide symporter (NIS) mediates iodide uptake into the thyroid. Because of this mechanism, differentiated thyroid cancer is susceptible for radioiodine therapy. Functional NIS expression in extrathyroidal tumors has been reported mainly in breast cancer. We screened colorecta