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Small-molecule costimulatory blockade: organic dye inhibitors of the CD40–CD154 interaction

✍ Scribed by Emilio Margolles-Clark; Oliver Umland; Norma S. Kenyon; Camillo Ricordi; Peter Buchwald


Book ID
105796870
Publisher
Springer
Year
2009
Tongue
English
Weight
337 KB
Volume
87
Category
Article
ISSN
0946-2716

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Organic dyes as small molecule protein–p
✍ Peter Buchwald; Emilio Margolles-Clark; Norma S. Kenyon; Camillo Ricordi 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 538 KB

## Abstract It is becoming increasingly clear that small molecules can often act as effective protein–protein interaction (PPI) inhibitors, an area of increasing interest for its many possible therapeutic applications. We have identified several organic dyes and related small molecules that (i) con