Small molecule compounds targeting the p53 pathway: are we finally making progress?

Small molecule agents targeting the p53-

Small molecule agents targeting the p53-MDM2 pathway for cancer therapy

✍ Weisi Wang; Yongzhou Hu 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 494 KB

## Abstract The powerful tumor suppressor p53 takes charge of a regulatory network to guard over the living cells from harmful effect of different forms of stress and eradicate the tumor cells for normal physiological condition maintenance. However the antitumor function of p53 is often attenuated