CO2 inhibits specific inward rectifier K
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Guoyun Zhu; Congxiao Liu; Zhiqiang Qu; Sengthong Chanchevalap; Haoxing Xu; Chun
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Article
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2000
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John Wiley and Sons
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English
⚖ 278 KB
Hypercapnia has been shown to affect cellular excitability by modulating K(+) channels. To understand the mechanisms for this modulation, four cloned K(+) channels were studied by expressing them in Xenopus oocytes. Exposures of the oocytes to CO(2) for 4-6 min produced reversible and concentration-