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Small compound inhibitors of basal glucose transport inhibit cell proliferation and induce apoptosis in cancer cells via glucose-deprivation-like mechanisms

โœ Scribed by Yi Liu; Weihe Zhang; Yanyan Cao; Yan Liu; Stephen Bergmeier; Xiaozhuo Chen


Book ID
116335509
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
979 KB
Volume
298
Category
Article
ISSN
0304-3835

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โœ Chih-Hsiung Wu; Yuan-Soon Ho; Chia-Yi Tsai; Ying-Jan Wang; How Tseng; Po-Li Wei; ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 700 KB

## Abstract Phloretin (Ph), a natural product found in apples and pears with glucose transporter (GLUT) inhibitory activity, exerts antitumor effects. However, little is known about its effects on human liver cancer. The purpose of this study is to test the cytotoxic effects of Ph on HepG2 cells an