SMALL-CELL CARCINOMA OF THE BRONCHUS
โ Scribed by Hansen, HeineH.; Hansen, Mogens; Rrth, Mikael; Dombernowsky, Per
- Book ID
- 122665102
- Publisher
- The Lancet
- Year
- 1980
- Tongue
- English
- Weight
- 161 KB
- Volume
- 315
- Category
- Article
- ISSN
- 0140-6736
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Fifty-four patients whose disease had been staged as extensive small cell carcinoma of the bronchus were randomised to receive either CAV1 (cyclophosphamide 600 mg m-2 i.v., adriamycin 50 mg m-2 i.v., given on day 1, and etoposide 500 mg m-2 p.o. given on day 3) or CAV5 (cyclophosphamide and adriamy
In small-cell carcinoma of the bronchus, extension to the brain is common. The role of prophylactic whole-brain irradiation and combination chemotherapy using CCNU in the prevention of brain extension is examined in the light of recent studies.