Small bowel adenocarcinoma in Crohn's disease
β Scribed by Richard C. Feldstein; Shivani Sood; Seymour Katz
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 67 KB
- Volume
- 14
- Category
- Article
- ISSN
- 1078-0998
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β¦ Synopsis
Small bowel neoplastic disease is a rare but dreaded occurrence in Crohn's disease (CD) and the diagnosis is often disguised by nonspecific and varied presenting symptoms mimicking active or obstructive CD. As such, the diagnosis is all too often delayed, typically detected at a late stage, and with a poor prognosis. CD has become a wellrecognized risk factor for the development of small bowel adenocarcinoma. The data, however, are limited and based on case reports, retrospective studies, and review of the literature.
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The substantial morbidity and mortality associated with Crohn's disease underlines the importance of accurate assessment at presentation, during follow-up, when investigating complications, and when evaluating the response to therapeutic interventions. Accurate methods are required to quantify the s
Background: Adenocarcinoma arising from perianal fistulae in patients with Crohn's disease (CD) is rare. The literature consists mainly of case reports and small series making characterization of this clinical entity difficult. We present 6 patients with CD and fistula-associated anal adenocarcinoma