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Smad7, an inhibitory smad, is differentially regulated by TGFb and activin in mouse granulosa cells

✍ Scribed by E. McGee; X. Gong; J. Wang

Book ID: 116475801
Publisher: Elsevier Science
Year: 2009
Tongue: English
Weight: 40 KB
Volume: 92
Category: Article
ISSN: 1556-5653
DOI: 10.1016/j.fertnstert.2009.07.1347

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## Abstract ## Objective Bone morphogenetic protein (BMP) and transforming growth factor β (TGFβ) are potent anabolic factors in adult articular chondrocytes. In this study, we investigated whether intracellular inhibitors of BMP and TGFβ signaling, inhibitory Smad6 (I‐Smad6) and I‐Smad7, are expr