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Slug Is a Mediator of Epithelial–Mesenchymal Cell Transformation in the Developing Chicken Heart

✍ Scribed by Laura A. Romano; Raymond B. Runyan

Book ID
115598136
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
562 KB
Volume
212
Category
Article
ISSN
0012-1606

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During early development, progenitors of the heart valves and septa are formed by epithelial-mesenchymal transformation (EMT) of endothelial cells in the atrioventricular (AV) canal. Previously, we showed that pertussis toxin, a specific inhibitor of a subset of G proteins, inhibited EMT in chick AV