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SLP76 and SLP65: complex regulation of signalling in lymphocytes and beyond

✍ Scribed by Koretzky, Gary A.; Abtahian, Farhad; Silverman, Michael A.

Book ID
109955284
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
628 KB
Volume
6
Category
Article
ISSN
1474-1741

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SLP-76 and LAT are two recently identified adapter proteins that are involved in the signal transduction cascade initiated by engagement of the TCR. The role of these two molecules in thymocyte development has become clearer following studies of gene targeted mice. The data indicate that SLP-76 and