Slow release of molecules in self-assembling peptide nanofiber scaffold
β Scribed by Yusuke Nagai; Larry D. Unsworth; Sotirios Koutsopoulos; Shuguang Zhang
- Book ID
- 113691294
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 433 KB
- Volume
- 115
- Category
- Article
- ISSN
- 0168-3659
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Traumatic brain injury (TBI) or brain surgery may cause extensive loss of cerebral parenchyma. However, no strategy for reconstruction has been clinically effective. Our previous study had shown that self-assembling peptide nanofiber scaffold (SAPNS) can bridge the injured spinal cord, elicit axon r
## Abstract RADARADARADARADA (RADA16βI) peptide, consisting of 16 alternating hydrophobic and hydrophilic (also alternating negative and positive charges) amino acids, forms extremely stable Ξ²βpleated sheet structure and then selfβassembles into nanofibers to produce highβorder interwoven nanofiber