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Slow exponential decay of rate of superoxide production in phorbol ester-activated human neutrophils

✍ Scribed by Kenneth Wong; Christina Chew


Book ID
105004168
Publisher
Springer
Year
1985
Tongue
English
Weight
585 KB
Volume
9
Category
Article
ISSN
0360-3997

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We have shown that platelet-activating factor (PAF), a weak primary stimulus for neutrophil superoxide generation, synergistically enhances neutrophil oxidative responses to the tumor promoter phorbol myristate acetate (PMA). Since PMA is known to cause cytosol-to-membrane shift of calcium-activated