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SLIT2 promoter methylation analysis in neuroblastoma, Wilms' tumour and renal cell carcinoma

โœ Scribed by Astuti, D; da Silva, N F; Dallol, A; Gentle, D; Martinsson, T; Kogner, P; Grundy, R; Kishida, T; Yao, M; Latif, F


Book ID
109997855
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
147 KB
Volume
90
Category
Article
ISSN
0007-0920

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CpG methylation in the promoter region has been shown to be important in the regulation of genes implicated in malignant transformation. The present study was designed to test the hypothesis that CpG methylation of the promoter region of the E-cadherin gene may inactivate its expression in renal cel