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Slipping up: Partial substrate degradation by ATP-dependent proteases

โœ Scribed by Nassif, Nicholas D.; Cambray, Samantha E.; Kraut, Daniel A.


Book ID
127312827
Publisher
John Wiley and Sons
Year
2014
Tongue
English
Weight
579 KB
Volume
66
Category
Article
ISSN
1521-6543

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Escherichia coli Lon exhibits a varying degree of energy requirement toward hydrolysis of different substrates. Efficient degradation of protein substrates requires the binding and hydrolysis of ATP such that the intrinsic ATPase of Lon is enhanced during protein degradation. Degradation of syntheti