SLICK — Scoring and Energy Functions for Protein—Carbohydrate Interactions.
✍ Scribed by Andreas Kerzmann; Dirk Neumann; Oliver Kohlbacher
- Publisher
- John Wiley and Sons
- Year
- 2006
- Weight
- 8 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0931-7597
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Protein design methods have been originally developed for the design of monomeric proteins. When applied to the more challenging task of protein–protein complex design, these methods yield suboptimal results. In particular, they often fail to recapitulate favorable hydrogen bonds and el
## Abstract We present an automated docking protocol specifically optimized to predict the structure and affinity of a protein–carbohydrate complex. A scoring function was developed based on a training set of 30 protein–carbohydrate complexes of known structure and affinity. Combinations of several