Clinical assessment of CYP2D6-mediated h
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Bill J. Gurley; Ashley Swain; Martha A. Hubbard; D. Keith Williams; Gary Barone;
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Article
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2008
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John Wiley and Sons
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English
β 569 KB
## Abstract Cytochrome P450 2D6 (CYP2D6), an important CYP isoform with regard to drugβdrug interactions, accounts for the metabolism of βΌοΈ30% of all medications. To date, few studies have assessed the effects of botanical supplementation on human CYP2D6 activity __in vivo__. Six botanical extracts