Sleep, Neuronal Plasticity and Brain Function

✍ Scribed by Peter Meerlo, Ruth M. Benca, Ted Abel (eds.)

• Publisher: Springer-Verlag Berlin Heidelberg
• Year: 2015
• Tongue: English
• Leaves: 561
• Series: Current Topics in Behavioral Neurosciences 25
• Edition: 1
• Category: Library

✦ Synopsis

This book reviews current knowledge on the importance of sleep for brain function, from molecular mechanisms to behavioral output, with special emphasis on the question of how sleep and sleep loss ultimately affect cognition and mood. It provides an extensive overview of the latest insights in the role of sleep in regulating gene expression, synaptic plasticity and neurogenesis and how that in turn is linked to learning and memory processes. In addition, readers will learn about the potential clinical implications of insufficient sleep and discover how chronically restricted or disrupted sleep may contribute to age-related cognitive decline and the development of psychiatric disorders such as schizophrenia and depression. The book consists of 19 chapters, written by experts in basic sleep research and sleep medicine, which together cover a wide range of topics on the importance of sleep and consequences of sleep disruption. This book will be of interest to students, researchers and clinicians with a general interest in brain function or a specific interest in sleep.

✦ Table of Contents

Front Matter....Pages i-x
Behavioral and Electrophysiological Correlates of Sleep and Sleep Homeostasis....Pages 1-24
Genetic Dissection of Sleep Homeostasis....Pages 25-63
Sleep Deprivation and Gene Expression....Pages 65-90
Sleep and Synaptic Homeostasis....Pages 91-121
Sleep and Synaptic Plasticity in the Developing and Adult Brain....Pages 123-149
Sleep and Adult Neurogenesis: Implications for Cognition and Mood....Pages 151-181
Animal Studies on the Role of Sleep in Memory: From Behavioral Performance to Molecular Mechanisms....Pages 183-206
A Bird’s Eye View of Sleep-Dependent Memory Consolidation....Pages 207-237
Neuroimaging Studies of Sleep and Memory in Humans....Pages 239-268
The Role of Sleep in Human Declarative Memory Consolidation....Pages 269-306
Sleep-Dependent Memory Consolidation in Healthy Aging and Mild Cognitive Impairment....Pages 307-330
Adenosine, Caffeine, and Performance: From Cognitive Neuroscience of Sleep to Sleep Pharmacogenetics....Pages 331-366
Optogenetic Control of Hypocretin (Orexin) Neurons and Arousal Circuits....Pages 367-378
Stress, Arousal, and Sleep....Pages 379-410
Sleep and Emotional Functions....Pages 411-431
Sleep and Plasticity in Schizophrenia....Pages 433-458
Chronically Restricted or Disrupted Sleep as a Causal Factor in the Development of Depression....Pages 459-481
Sleep Deprivation Therapy for Depression....Pages 483-502
Pharmacological Treatment of Sleep Disorders and Its Relationship with Neuroplasticity....Pages 503-553
Back Matter....Pages 555-559

✦ Subjects

Neurosciences; Behavioral Sciences; Psychiatry; Neurology