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Sleep-Disordered Breathing in Prader-Willi Syndrome and its Association with Neurobehavioral Abnormalities

✍ Scribed by F.J. O'Donoghue; D. Camfferman; J.D. Kennedy; A.J. Martin; T. Couper; L.D. Lack; K. Lushington; R.D. McEvoy

Book ID
116683536
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
146 KB
Volume
147
Category
Article
ISSN
1097-6833

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✍ Dederieke A.M. Festen; Maaike Wevers; Al W. de Weerd; Renilde A.S. van den Bossc πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 143 KB πŸ‘ 2 views

## Abstract Prader–Willi syndrome (PWS) is characterized by hypotonia, hypogonadism, obesity, and short stature. Neurobehavioral abnormalities, cognitive impairment, and sleep‐related breathing disorders (SRBD) are common. In the general population associations between neurobehavioral and cognitive

Relationship of sleep abnormalities to p
Relationship of sleep abnormalities to patient genotypes in Prader-Willi syndrome
✍ Vgontzas, Alexandros N.; Kales, Anthony; Seip, James; Mascari, Maria J.; Bixler, πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 581 KB

To assess whether sleep abnormalities are related to the genetic abnormalities in Prader-Willi Syndrome (PWS), we performed polysomnographic studies (nighttime and daytime) and determined the chromosome 15 genotypes in eight patients with PWS. Four patients demonstrated sleep onset REM periods (SORE