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SLC39A2andFSIP1polymorphisms as potential modifiers of arsenic-related bladder cancer

โœ Scribed by Margaret R. Karagas; Angeline S. Andrew; Heather H. Nelson; Zhongze Li; Tracy Punshon; Alan Schned; Carmen J. Marsit; J. Steven Morris; Jason H. Moore; Anna L. Tyler; Diane Gilbert-Diamond; Mary-Lou Guerinot; Karl T. Kelsey


Book ID
106135211
Publisher
Springer
Year
2011
Tongue
English
Weight
389 KB
Volume
131
Category
Article
ISSN
0340-6717

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## Abstract Hereditary nonpolyposis colorectal cancer (HNPCC) is characterized by germline mutations in DNA mismatch repair genes; however, variation in disease expression suggests that there are potential modifying factors. Polymorphisms of the __HFE__ gene, which cause the iron overload disorder