Skin lymphoma: the illustrated guide

✍ Scribed by Cerroni, Lorenzo

• Publisher: John Wiley & Sons
• Year: 2020
• Tongue: English
• Leaves: 584
• Edition: Fifth edition
• Category: Library

✦ Synopsis

"Many things have changed since 2014, when I completed the previous edition of this book. The World Health Organization (WHO) published in 2017 an update of the Classification of Tumours of Haematopoietic and Lymphoid Tissues, and in 2019 the European Organization for Research and Treatment of Cancer (EORTC), together with a WHO panel, published the first update since 2005 of the Classification of cutaneous lymphomas. In the new classifications all entities of cutaneous lymphomas have been updated, and some new ones were added. In this context, the book has been modified to reflect the new classification schemes. Molecular data are being increasingly used for diagnosis and classification of haematological malignancies, particularly for precise categorization of leukemias. On the other hand, access to state-of-the-art molecular techniques is still very limited: in fact, the vast majority of colleagues who report cases of cutaneous lymphoproliferative disorders make diagnoses based mostly on histopathological and phenotypical features combined with clinical aspects, thus the core of the book is still focused on a traditional clinicopathological approach to diagnosis. All relevant molecular data, of course, are discussed as well"--

✦ Table of Contents

Half Title......Page 2
Title Page......Page 3
Copyright......Page 4
Dedication......Page 5
Contents......Page 6
List of teaching cases......Page 9
Preface......Page 10
Acknowledgments......Page 12
Examination of patients......Page 13
Histopathology, immunophenotype, and molecular genetics......Page 16
Other methods used in the study of cutaneous lymphoid infiltrates......Page 22
Pseudomalignancy, premalignancy, and early malignancy......Page 23
References......Page 24
Chapter 2 The “parapsoriases”: a riddle, wrapped in a mystery, inside an enigma......Page 26
References......Page 33
Chapter 3 Mycosis fungoides......Page 34
Onset of mycosis fungoides or exacerbation of undiagnosed disease under treatment with immunomodulatory agents......Page 35
Clinical features......Page 37
Association with other diseases......Page 41
Histopathology, immunophenotype, and molecular genetics......Page 43
Histopathologic differential diagnosis from inflammatory conditions......Page 62
Clinical and histopathologic variants......Page 64
Prognosis......Page 102
References......Page 111
Chapter 4 Seary syndrome......Page 124
Onset/progression under systemic therapies for benign inflammatory dermatoses......Page 125
Clinical features......Page 126
Histopathology, immunophenotype, and molecular genetics......Page 128
Treatment......Page 134
Prognosis......Page 135
References......Page 139
Chapter 5 Primary cutaneous CD30+ lymphoproliferative disorders......Page 144
Clinical features......Page 147
Histopathology, immunophenotype, and molecular genetics......Page 148
Clinicopathologic differential diagnosis......Page 157
Treatment......Page 158
Histopathology, immunophenotype, and molecular genetics......Page 165
Treatment......Page 173
Prognosis......Page 175
References......Page 184
Chapter 6 Subcutaneous panniculitis‐like T‐cell lymphoma......Page 191
Clinical features......Page 192
Histopathology, immunophenotype, and molecular genetics......Page 193
Differential diagnosis with other cutaneous NK/T‐cell lymphomas with prominent involvement of the subcutaneous tissue......Page 195
Differential diagnosis with lupus panniculitis......Page 196
Prognosis......Page 198
References......Page 203
Chapter 7 Aggressive cutaneous cytotoxic lymphomas......Page 206
Clinical features......Page 207
Histopathology, immunophenotype, and molecular genetics......Page 208
Clinical features......Page 214
Histopathology, immunophenotype, and molecular genetics......Page 215
Treatment......Page 218
Prognosis......Page 219
Histopathology, immunophenotype, and molecular genetics......Page 220
Treatment......Page 224
Prognosis......Page 225
References......Page 227
Clinical features......Page 230
Histopathology, immunophenotype, and molecular genetics......Page 232
Prognosis......Page 236
References......Page 237
Chapter 9 Cutaneous CD4+ small/medium T‐cell lymphoproliferative disorder......Page 239
Treatment......Page 240
Prognosis......Page 241
Final considerations......Page 243
References......Page 244
Histopathology, immunophenotype, and molecular genetics......Page 246
Prognosis......Page 247
References......Page 249
Histopathology, immunophenotype, and molecular genetics......Page 250
Treatment and prognosis......Page 252
References......Page 253
Clinical features, histopathology, immunophenotype, and molecular genetics......Page 254
Treatment and prognosis......Page 257
Clinical features, histopathology, immunophenotype, and molecular genetics......Page 258
Treatment and prognosis......Page 259
References......Page 261
Clinical features......Page 265
Histopathology, immunophenotype, and molecular genetics......Page 267
Differential diagnosis of cutaneous follicle center lymphoma, diffuse type, from cutaneous diffuse large B‐cell lymphoma, leg t......Page 277
Prognosis......Page 278
References......Page 281
Chapter 14 Cutaneous marginal zone lymphoma (cutaneous MALT lymphoma) and variants......Page 284
Clinical features......Page 287
Histopathology, immunophenotype, and molecular genetics......Page 288
Prognosis......Page 296
Clinical features......Page 297
Histopathology, immunophenotype, and molecular genetics......Page 298
Prognosis......Page 299
Histopathology, immunophenotype, and molecular genetics......Page 300
Histopathology, immunophenotype, and molecular genetics......Page 302
Treatment and prognosis......Page 303
Clinical features......Page 304
References......Page 305
Chapter 15 Cutaneous diffuse large B‐cell lymphoma, leg type......Page 309
Clinical features......Page 310
Histopathology, immunophenotype, and molecular genetics......Page 311
Treatment......Page 318
Prognosis......Page 319
References......Page 322
Chapter 16 Intravascular large cell lymphomas......Page 325
Histopathology, immunophenotype, and molecular genetics......Page 326
Intravascular large B‐cell lymphoma colonizing hemangiomas......Page 328
Treatment and prognosis......Page 329
References......Page 333
Clinical features......Page 336
Treatment and prognosis......Page 337
Histopathology, immunophenotype, and molecular genetics......Page 339
Treatment and prognosis......Page 340
Histopathology, immunophenotype, and molecular genetics......Page 341
Treatment and prognosis......Page 343
Clinical features......Page 344
Treatment and prognosis......Page 345
Histopathology, immunophenotype, and molecular genetics......Page 347
Treatment and prognosis......Page 349
Histopathology, immunophenotype, and molecular genetics......Page 350
Treatment and prognosis......Page 351
Histopathology, immunophenotype, and molecular genetics......Page 352
Treatment and prognosis......Page 354
Histopathology, immunophenotype, and molecular genetics......Page 355
Histopathology, immunophenotype, and molecular genetics......Page 356
Treatment and prognosis......Page 357
Clinical features......Page 358
Treatment and prognosis......Page 359
References......Page 362
Chapter 18 Cutaneous lymphomas in immunosuppressed individuals......Page 366
Histopathology, immunophenotype, and molecular genetics......Page 367
Treatment and prognosis......Page 372
Treatment and prognosis......Page 374
CUTANEOUS LYMPHOPROLIFERATIVE DISORDERS IN OTHER IATROGENIC AND NON‐IATROGENIC IMMUNE DEFICIENCIES......Page 377
Treatment and prognosis......Page 378
References......Page 381
Clinical features......Page 386
Histopathology, immunophenotype, and molecular genetics......Page 387
PROGRESSION TO DIFFUSE LARGE B‐CELL LYMPHOMA (RICHTER SYNDROME)......Page 392
References......Page 395
Clinical features......Page 397
Histopathology, immunophenotype, and molecular genetics......Page 398
Immunophenotype......Page 401
Treatment and prognosis......Page 404
References......Page 412
Clinical features......Page 414
Histopathology, immunophenotype, and molecular genetics......Page 415
Immunophenotype......Page 418
Prognosis......Page 421
MATURE PLASMACYTOID DENDRITIC CELL PROLIFERATIONS ASSOCIATED WITH MYELOID NEOPLASMS......Page 422
References......Page 423
Chapter 22 Cutaneous manifestations of other leukemias......Page 426
References......Page 429
Clinical features......Page 431
Histopathology, immunophenotype, and molecular genetics......Page 432
Histopathology, immunophenotype, and molecular genetics......Page 435
Treatment and prognosis......Page 436
References......Page 439
Histopathology, immunophenotype, and molecular genetics......Page 442
Treatment and prognosis......Page 444
References......Page 447
Chapter 25 Cutaneous composite lymphomas......Page 448
Histopathology, immunophenotype, and molecular genetics......Page 449
References......Page 453
Chapter 26 Nonneoplastic cutaneous signs of systemic lymphomas......Page 455
References......Page 464
Chapter 27 Cutaneous lymphomas in children and adolescents......Page 466
References......Page 473
Chapter 28 Pseudolymphomas of the skin......Page 477
Lupus panniculitis......Page 513
Other pseudolymphomas associated with cutaneous lupus erythematosus......Page 515
References......Page 558
Chapter 29 The cutaneous “atypical lymphoid proliferation”......Page 566
References......Page 568
Index......Page 569