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Skeletal myogenesis in the mouse esophagus does not occur through transdifferentiation

✍ Scribed by Mark Rishniw; Hong-Bo Xin; Ke-Yu Deng; Michael I. Kotlikoff

Publisher: John Wiley and Sons
Year: 2003
Tongue: English
Weight: 131 KB
Volume: 36
Category: Article
ISSN: 1526-954X
DOI: 10.1002/gene.10198

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✦ Synopsis

Abstract

Summary: To determine the developmental history of murine esophageal skeletal muscle, smooth muscle cells were fate mapped by lineage‐specific recombination and phenotypically marked by eGFP. Examination of embryonic and postnatal tissues revealed that esophageal skeletal muscle does not arise from transdifferentiation of committed smooth muscle cells. genesis 36:81–82, 2003. © 2003 Wiley‐Liss, Inc.

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