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Skeletal muscle-specific expression of a utrophin transgene rescues utrophin-dystrophin deficient mice

โœ Scribed by Rafael, Jill A.; Tinsley, Jonathon M.; Potter, Allyson C.; Deconinck, Anne E.; Davies, Kay E.


Book ID
109916068
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
600 KB
Volume
19
Category
Article
ISSN
1061-4036

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Expression of Utrophin at Dystrophin-Def
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## Abstract In __mdx__ mice, intrinsic laryngeal muscles are spared and sternomastoid muscles are affected, showing cycles of muscle regeneration. We observed that utrophin and acetylcholine receptors are fragmented only in affected muscles, providing further evidence that changes in the overall di