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Skeletal muscle autophagy and apoptosis during aging: Effects of calorie restriction and life-long exercise

✍ Scribed by Stephanie Eva Wohlgemuth; Arnold Young Seo; Emanuele Marzetti; Hazel Anne Lees; Christiaan Leeuwenburgh


Book ID
113615322
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
627 KB
Volume
45
Category
Article
ISSN
0531-5565

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## Abstract Aging enhances apoptosis of hepatocytes under normal physiological conditions and increases the susceptibility to apoptosis of hepatocytes, whereas chronic calorie restriction (CR) suppresses the age‐enhanced susceptibility to apoptosis. To clarify the subcellular mechanisms of age‐asso