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Skeletal effects of growth hormone and IGF-I in adults

✍ Scribed by Robert Marcus

Publisher
Springer
Year
1997
Tongue
English
Weight
347 KB
Volume
7
Category
Article
ISSN
0969-711X

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Deficiencies in either growth hormone (GH) or insulin-like growth factor 1 (IGF-1) are associated with reductions in bone size during growth in humans and animal models. Liver-specific IGF-1-deficient (LID) mice, which have 75% reductions in serum IGF-1, were created previously to separate the effec