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Skeletal and hematopoietic defects in mice transgenic for collagen X

โœ Scribed by O. Jacenko; D. Chen; S. Ito; J. Bateman; B.R. Olsen


Book ID
117640588
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
104 KB
Volume
16
Category
Article
ISSN
0945-053X

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Skeletal development of transgenic mice with a type II collagen mutation was analyzed and compared with wild-type littermates. The single base substitution in Col2a1 resulted in a glycine to serine mutation within the helical domain and corresponded to one previously identified in a patient with the